【公開日:2024.01.04】【最終更新日:2023.12.13】
課題データ / Project Data
課題番号 / Project Issue Number
22KU1053
利用課題名 / Title
Immobilization of proteins with coordination cages
利用した実施機関 / Support Institute
九州大学 / Kyushu Univ.
機関外・機関内の利用 / External or Internal Use
内部利用(ARIM事業参画者以外)/Internal Use (by non ARIM members)
技術領域 / Technology Area
【横断技術領域 / Cross-Technology Area】(主 / Main)物質・材料合成プロセス/Molecule & Material Synthesis(副 / Sub)-
【重要技術領域 / Important Technology Area】(主 / Main)次世代バイオマテリアル/Next-generation biomaterials(副 / Sub)次世代ナノスケールマテリアル/Next-generation nanoscale materials
キーワード / Keywords
バイオアダプティブ材料/ Bioadaptive materials,ナノ多孔体/ Nanoporuous material,ナノ粒子/ Nanoparticles
利用者と利用形態 / User and Support Type
利用者名(課題申請者)/ User Name (Project Applicant)
Le Ouay Benjamin
所属名 / Affiliation
九州大学大学院理学研究院化学部門
共同利用者氏名 / Names of Collaborators in Other Institutes Than Hub and Spoke Institutes
ARIM実施機関支援担当者 / Names of Collaborators in The Hub and Spoke Institutes
利光 史行
利用形態 / Support Type
(主 / Main)機器利用/Equipment Utilization(副 / Sub)-
利用した主な設備 / Equipment Used in This Project
報告書データ / Report
概要(目的・用途・実施内容)/ Abstract (Aim, Use Applications and Contents)
S.tudy of the confromational changes of proteins upon immobilization with coordination cgaes.
実験 / Experimental
Protein solutions and composites suspension were analyzed by Circular dichroism (CD).
結果と考察 / Results and Discussion
T.e signal of free proteins was observes, in agreement with literature. However, composites did not show any signal, despite our best effort. This was attributed to an internal filter effect, related to the very high absorbance of cages (e > 100 000 per M per cm) in the relevant spectral range.In conclusion, circular dichroism was not a suitable technique to analyze this system. The measurement helped us convince the reviewers of this fact.
図・表・数式 / Figures, Tables and Equations
その他・特記事項(参考文献・謝辞等) / Remarks(References and Acknowledgements)
成果発表・成果利用 / Publication and Patents
論文・プロシーディング(DOIのあるもの) / DOI (Publication and Proceedings)
口頭発表、ポスター発表および、その他の論文 / Oral Presentations etc.
特許 / Patents
特許出願件数 / Number of Patent Applications:0件
特許登録件数 / Number of Registered Patents:0件